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Download PDF by Paul F. Torrence: Antiviral Drug Discovery for Emerging Diseases and

By Paul F. Torrence

ISBN-10: 0471668273

ISBN-13: 9780471668275

ISBN-10: 0471716707

ISBN-13: 9780471716709

Antiviral Drug Discovery offers readers a state-of-the-art view of the way chemical options are being mobilized to increase novel ways that might successfully confront rising ailments and biowarfare. among the subject matters mentioned are smallpox, the Ebola virus, influenza, SARS, arenaviruses and flaviviruses. each one bankruptcy discusses hypothetical recommendations for the invention of suitable antiviral brokers, contemporary findings relating to biochemistry or drug discovery, and advances within the extra improvement of validated leads within the region. well timed and informative, this publication sincerely delineates the efforts being made to advance new and powerful broad-spectrum antiviral brokers.

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Extra resources for Antiviral Drug Discovery for Emerging Diseases and Bioterrorism Threats

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The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3. J. Virol. 2003, 77, 7945–7956. 17. ; Mahanty, S. Ebola hemorrhagic fever and septic shock. J. Infect. Dis. 2003, 188, 1613–1617. 18. Geisbert, T. ; Hensley, L. ; Young, H. ; Reed, D. ; Geisbert, J. ; Scott, D. ; Jahrling, P. ; Davis, K. J. Pathogenesis of Ebola hemorrhagic fever in cynomolgus macaques. Am. J. Pathol. 2003, 163, 2347–2370. 19. ; Bray, M. Pathogenesis of filoviral hemorrhagic fevers. Lancet Infect.

5. Eitzen, E. M. Use of biological weapons. In Textbook of Military Medicine, Office of the Surgeon General, Department of the Army, Washington, DC, 1997, pp. 437–450. 6. Eitzen, E. ; Takafuji, E. Historical overview of biological warfare. In Textbook of Military Medicine, Office of the Surgeon General, Department of the Army, Washington, DC, 1997, pp. 415–436. 7. ; Lillibridge, S. ; Ostroff, S. ; Hughes, J. M. Public health assessment of potential biological terrorism agents. Emerging Infect. Dis.

Html Public Broadcasting System. se/cbw/ St. Louis University. edu/colleges/sph/bioterrorism/ Stimson Center Report No. S. S. Department of State. 1 INTRODUCTION Emerging pathogens and the threat of bioterrorism are inherent elements of modern civilization. A variety of activities, including the expansion of human populations into new geographical areas, may result in contact with novel microbes and their rapid distribution by global transportation systems. 1 Terrorists have not yet released a pathogenic virus, but the potentially devastating consequences of such an event make it essential to recognize our vulnerability and develop effective countermeasures.

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Antiviral Drug Discovery for Emerging Diseases and Bioterrorism Threats by Paul F. Torrence

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